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Novartis CAR-T therapy second-line NHL breaks down

 Last Update: 2021-10-02
 Source: Internet
 Author: User

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Novartis today announced the results of its CAR-T therapy Kymriah in a second-line B-cell NHL phase III clinical trial

Drug source analysis

Kymriah is the first CAR-T therapy to be marketed.

But the durability of CAR-T has always been a problem

About half of B-cell NHL patients tolerate first-line therapy or progress within 12 months, and the standard therapy after progression is stem cell transplantation after high-dose chemotherapy

The market of CAR-T therapy is mainly based on its amazing response rate, but this response rate may be exaggerated due to uncontrolled trials

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