Not only cephalosporin, you can't drink alcohol when you take these medicines! Beware of the risk of death

"Cephalosporin is wine, just go"

This phrase is often said in jokes

Actually, a lot of people don't do it right

But sometimes it's really not a joke

Why is "cephalosporin + wine" likely to kill people?

The culprit behind it is the disulfiram reaction!

Disulfiram reaction

Refers to drinking alcohol or drinking alcoholic beverages after taking certain drugs, and after a series of reactions, resulting in "acetaldehyde accumulation" in the body, resulting in poisoning reactions
.

Symptoms of intoxication

Generally, it appears within 15~30 minutes of drinking or drinking after medication, including facial flushing, eye congestion, blurred vision, headache, dizziness, nausea, vomiting, sweating, dry mouth, chest pain, etc
.

Lead to consequences

Severe cases can lead to myocardial infarction, acute heart failure, acute liver injury, convulsions (convulsions) and death
.
The elderly, children, patients with cardiovascular and cerebrovascular diseases, and people with alcohol allergies are
at greater risk.
What should I do if I accidentally drink alcohol after eating cephalosporin?

1 observation

Stop drinking alcohol and watch for a while to see if you experience
discomfort.
If there is no discomfort, the problem is not great
.
If there is a severe discomfort reaction, such as difficulty breathing, seek medical attention
promptly.

2.
Induce vomiting

If you can immediately realize that alcohol is taken with drugs such as cephalosporin, you can try to induce vomiting and spit out the contents of your stomach, which may reduce the chance
of accidents.

3.
Drink water

You can try to drink plenty of water to dilute the alcohol concentration and speed up alcohol metabolism
.

Note: Inducing vomiting and drinking water presupposes mild symptoms, and if breathing difficulties have occurred, blindly inducing vomiting or drinking water may cause suffocation
.

4V position

For patients who have difficulty breathing or even coma shock, while dialing 120 for help in time, the people around them should untie the neckline of the patient's clothes or scarf so that they lie flat, raise their heads 10 to 15 degrees, raise their feet 20 to 30 degrees, and tilt their heads to one side
.

What drugs may cause this reaction?

Drugs that have been shown to cause disulfiram reactions are:

01 Cephalosporins:

Some drugs with the word "cephalosporin" in their names, such as cefoperazone, cefmandol, cefotiamander, cefonic, cefotetan, cefmetaxime and so on
.

Note: Some cephalosporins do not have a disulfiram reaction, but it is difficult for non-specialists to tell the difference, so it is best not to take
them with alcohol.

02Nitroimidazoles (antibiotics)

Metronidazole, tinidazole, ornidazole, etc
.

03Nitrofurans (antibiotics)

Nitrofurantoin, furazolidone, etc
.

04Hypoglycemic drugs (including insulin injection)

Glibenclamide, glipizide, gliclazide, gliququantel, glimepiride, phenmetformin, etc
.

Note: Hypoglycemic drugs taken with alcohol may also cause hypoglycemia
.

05 Other

Chloramphenicol, isoniazid (anti-tuberculosis drug), warfarin (anticoagulant), ketoconazole (antifungal), etc
.

Medication attention

The above drugs should not be taken within 24 hours after drinking, among them, do not drink alcohol
during the administration of antibiotics such as cephalosporin and within 7 days after stopping the drug.
For drugs that require long-term use, it is best to abstain from alcohol
.

In fact, not only alcohol, but also some foods and drugs containing alcohol may be encountered if you are not careful in life, we should also pay attention to:

Foods containing alcohol

Drunken shrimp drunken crab, wine heart chocolate, tofu milk, beer duck, etc
.

Medicines containing alcohol

Compound licorice oral liquid, Huoxiang zhengqi water, injection of some drugs, some cosmetics applied to the skin, ointments, etc.
(see whether there is "alcohol" or "ethanol" in the ingredients before use).

What other medicines cannot be taken with alcohol?

In addition to drugs that may cause disulfiram reactions, there are drugs that can increase adverse reactions and even be dangerous if taken with alcohol:

01 Sleeping pills + alcohol - be careful not to wake up"

Including: phenobarbital, chloral hydrate, diazepam, chlordiazepam tablets, estazolam, zolpidem, etc
.

Reason: Sedative sleeping pills have an inhibitory effect on the brain, and alcohol will aggravate this inhibition, which may cause patients to have coma, shock, respiratory failure and other critical conditions
.

02 Analgesics + alcohol - "stomach bleeding" beckons to you

Including: aspirin, paracetamol, ibuprofen and other drugs
that have "pain-relieving" or "fever-reducing" effects.

Reason: This type of "non-steroidal anti-inflammatory drugs" mainly has some irritation to the gastric mucosa, and under the synergy of alcohol, the superposition of the two may cause gastric ulcers, gastritis, and even gastric bleeding
.

03 Blood pressure lowering drugs + alcohol - be wary of "hypotensive shock"

Includes: reserpine, captopril, nifedipine
.

Causes: Some antihypertensive drugs taken with alcohol may cause vasodilation, hypotension, and even shock, which is life-threatening
.
Some antihypertensive drugs taken with alcohol may cause blood pressure to soar, and severe cases can lead to cerebral hemorrhage
.

04 Antidepressants + wine - pour sorrow with wine

Including: sertraline, imipramine, amitriptyline, doxepin, fluvoxamine, citalopram, foroxetine, paroxetine, etc
.

Reason: Similar to sleeping drugs, taking with alcohol will increase the inhibitory effect on the brain center, and produce adverse reactions, and even reduce the efficacy and aggravate the condition
.

Is it feeling so much medicine

Can't remember, can't remember completely?

Never mind

Just remember

"Drink without medicine, take medicine without drinking"

That's enough

Resolutely do not drink alcohol while taking medicine

to ensure that nothing goes wrong