New study accurately identifies patients with colorectal cancer through analysis of the composition of the microbiome

Colorectal cancer (CRC) is a challenging public health problem facing the global population.

Accurately identify non-colorectal cancer patients through analysis of the composition of the microbiome

Image source: DOI: 10.

Epidemiological data show that due to the aging of the population and the increasing popularity of Western diets and life>

Researcher Kertu Liis Krigul said, however, the current screening program will face many challenges, including low participation rate, low sensitivity to precancerous or early cancer, and false positive and false negative results.

In this research report, the researchers tested the FIT tube used in the National Colorectal Cancer Screening Program in volunteers, and found that this test may be suitable for microbiome analysis; however, the collection method is used to detect cancer The actual ability of specific bacterial characteristics may be studied in people with or without colorectal cancer; researcher Krigul said that the use of additional microbiome-based biomarkers to detect colorectal cancer may be potential Make the diagnosis of colorectal cancer more sensitive and cost-effective

The researchers speculate that the stool samples from the FIT tube can also be used as a resource for biomarker research and be used to study the role of the gut microbiome in other digestive system diseases related to the gut microbiome.

In summary, the results of this article show that FIT tubes can be used to analyze the characteristics of microbial communities in colorectal cancer screening projects, which avoids the need to collect additional samples and may improve the sensitivity of colorectal cancer detection

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Original source:

Krigul, KL, Aasmets, O.