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Dopamine is an important signaling molecule in nerve cel.
A research team from Bochum, the University of Göttingen and Duisburg used modified carbon nanotubes that glow brighter in the presence of the messenger substance dopami.
These sensors visualize dopamine release from nerve cells with unprecedented clari.
Fluorescence changes in the presence of dopamine
The neurotransmitter dopamine controls the reward center of the bra.
This is where the new sensor comes into pl.
"We systematically changed this property by combining different short nucleic acid sequences with carbon nanotubes, which changed their fluorescence when they came into contact with specific molecules," explains Sebastian Kru.
Coating healthy nerve cells with a sensing layer
In order to do this, the sensors must be moved close to the functional neuron netwo.
They believe this new sensor has great potential: "They provide new insights into the plasticity and regulation of dopamine signaling," says Sofia Eizaro.