New risk factors for meningoma haemorrhage

Meningoma is a common benign tumor in the skull, accounting for 19% of primary brain tumors.
hemorrhagic rich in meningococ, but tumor bleeding is rare, with only 0.5%-2.4% of meningococ that are reported in the literature.
The largest study of meningioma haemorrhage to date, conducted by Bošnjak and others, found that the risk factors leading to meningioma haemorrhage include: age greater than 70 years old or younger than 30 years of age;
Analysis of a rare case of meningococid hemorrhage that broke into the lower cavity of the cobweb membrane accompanied by encephaloblast dilation by Elliot Pressman of the University of South Florida in the United States found that meningoencephaloma haemorrhage continued without any previously reported risk factors, suggesting two new factors that could cause hemorrhage in benign rock oblique meningococ?
results were published online november 2019 in World Neurosurgery.
study method 1 case of 56-year-old female patients, post-menoptosis to receive high-dose estrogen replacement therapy, accompanied by a stable chest aortic aneurysm history and history of depression, taking citopram 20 mg/day.
patients with GCS scores of 3 when first responders arrived after the onset of the disease, and were given glycol and highly permeable saline intravenous injections.
the left pupil 8mm after hospitalization, the light reflection disappears, the right pupil 3mm, the light reflection weakens.
CTA examination showed a 3.8×3.0cm reinforced stove in the left armpit, growing along a slope, compressing the brain dry (Figure 1A-B), hemorrhage in the subcab of the cobwebs in the saddle pool and the bridge front pool (Figure 1C-D), bleeding in the third chamber (Figure 1C), and a 3mm offset in the middle line.
the right side of the emergency department, the initial pressure measurement was about 10cmH₂O.
no aneurysms or hemangiomorphics were found in DSA angiitis, and angiofusy was visible in the sloped area of the rock, with dry dilation of the meninges pituitary glycation (Figure 1E).
1. Bleeding of a patient's meningococcuse in the rock slope.
the left side of the shin into the road joint b sinuses and then into the road to open the skull to remove most of the tumor.
was diagnosed as WHOI.grade meningioma with a MIB-1 proliferation index of 2%.
postoperative GCS score of 4, the 5th day after surgery to review the skull CT examination prompted the tumor sub-full cut (Figure 2A-B), the brain hematoma disappeared, the brain stem compression lifted, did not see the midline shift (2C-E).
postoperative DSA angioscopic examination suggests substrate arterial spasms (Figure 2F).
14 days after the bleeding, the patient died after removing the tracheal intage.
2. Postoperative imaging review of the second full excision of meningococcial tumors in the iwed area.
the results of the study, the patient had depression and was taking citopram.
previous studies have found that the use of selective 5-serotonin reuptake inhibitors (SSRIs) or other antidepressants increases the activity of 5-serotonin energy and increases the risk of spontaneous bleeding in meningomas.
, antidepressants can be thought to cause bleeding in the patient's meningioma.
In addition, patients are receiving high doses of estrogen replacement therapy before onset, whether using estrogen alone or estrogen plus progesterone patients, there is a risk of ischemic stroke, for meningioma patients, may promote acute ischemic meningioma, into in-tumor haemorrhage.
conclusion The authors conclude that spontaneous hemorrhage of meningioma is very rare, and that the risk factors leading to intrinsic hemorrhage may also cause intrinsic hemorrhage in meningioma, in addition to the previously reported factors such as high levels of tumor malignancy, fibrosis or angioblastular hyperplocial hyperplosomes, 5-oxysamine regulation therapy and high-dose estrogen replacement therapy may also cause intrinsic hemorrhage of meningioma, but this conclusion requires more clinical case data support and validation.
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