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The etiology of type 1 diabetes (T1D) is very complicated.
The genetic elicitor that induces the onset of type 1 diabetes may be in the lungs
Image source: Ho, D.
This may allow researchers to make unexpected discoveries, that is, the greatest impact may occur in the genes of the lungs; in this research report, the researchers revealed this association for the first time; we all know that the pancreas is involved in diabetes.
Researcher Daniel Ho and colleagues have developed a machine learning method that can find specific patterns in the genetic data of thousands of individuals (individuals with or without type 1 diabetes).
Type 1 diabetes is often found in childhood, which requires patients to inject insulin every day to control the progression of the disease.
In summary, the results of this article have determined the tissue-specific quantitative trait locus of SNPs associated with the onset of type 1 diabetes, and the strongest tissue-specific quantitative trait locus effect may be located in the lungs, which may help Explain the relationship between the body's respiratory tract infection and the risk of seroconversion of bait pancreatic islet autoantibodies
Note: The original text has been deleted
Original source:
Ho, D.