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New discoveries about the HIV life cycle

 Last Update: 2022-04-24
 Source: Internet
 Author: User

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HIV-1 dimer analysis

A global pandemic threatens people: HIV/AIDS

Critical stages of the viral life cycle can be attractive targets for drugs and treatments

a molecular switch

In the journal Nature Structural & Molecular Biology , researchers now describe a new technique to study the HIV-1 life cycle at single-nucleotide resolution

"In HIV-1 research, the idea that dimerization is a prerequisite for packaging has been discussed for a long time

Liqing Ye conducts research in Smith's lab at HIRI and is the lead author of the current study

The scientists discovered the sequence that regulates the balance between these two RNA conformations

"We hope to be able to apply these findings to RNA-based antiretroviral drugs or improved gene therapy vectors

Human immunodeficiency virus (HIV) belongs to the large family of retroviruses

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