New details of the incognito spread of HIV have been revealed

scientists have used computer models to crack new details about the spread of HIV between cells, Physicists Network reported Thursday. The report,
the U.S., says it will open up new avenues for developing AIDS drugs.
the key to HIV's success in long-term confrontations with humans is its trick of hiding itself in the human body. When HIV infects a cell, it forces the cell membrane on the surface of the host cell to form a small cystic membrane as its hiding place. The cystic membrane goes through a process known as "germination and reproduction", which is broken from the middle and drifts around, infecting more cells.
in previous studies, scientists only knew that the "germination and reproduction" process involved an HIV complex called Gag, but details of its involvement in HIV reproduction were unclear because existing imaging techniques made it difficult to photograph the compound's molecular level.
, a co-author of the paper and a professor of chemistry at the University of Chicago, and colleagues, created a computer model that simulates the activity of the Gag protein. They constantly adjusted the model until they obtained the chemical composition that best matched the "germination and reproduction" process, and in the model adjustment obtained structural units that had never been found in the Gag protein, which played a very important role in the process of self-assembling the Gag protein and applying small tricks to reproduce incognito.
computer-simulated the chemical composition that best matches the "germination and reproduction" process, the Voss team worked with scientists at the National Institutes of Health to successfully validate the simulation results in the lab. Voss said the study not only validates the potential of computer models to be used in simulated viruses, but also opens up new avenues for AIDS prevention and treatment by developing drugs that prevent the accumulation of Gag proteins in the body and inhibit the spread and reproduction of HIV. (Source: Science and Technology Daily, Yu Cuijuan)