New coronavirus attacks part of the metabolic process in the lungs revealed

According to a recent report by the physicist organization network, recently, researchers at the Karolinska Institute in Sweden have determined part of the metabolic process of the new coronavirus attacking lung tissue

During the COVID-19 pandemic, patients with cardiovascular diseases and obese people are at a much higher risk of severe and even fatal COVID-19 pneumonia

Observational studies on patients with new coronary pneumonia have shown that there is a correlation between the severity of the disease and the metabolic disorder of high levels of lipids (fats) in the blood

Researchers at Karolinska Institute checked which parts of the cellular energy supply are particularly important to the new coronavirus and how they affect the severity of the disease

Researchers have found that when the new coronavirus infects lung cells, glycolysis and glutamine decomposition are the "preferred" metabolic pathways of the virus, which play an important role in its spread and growth, and are the keys to cell energy supply and function.

One of the authors of the paper and a researcher at the Department of Laboratory Medicine of Karolinska Institutet, said: "By blocking these pathways, we can limit the production of viruses

The key to this research is the discovery of biomarkers of disease severity

"The changes in these metabolites may have lasting effects on insulin resistance, neurocognitive impairment, and organ failure

This result is based on the analysis of blood samples from 41 patients with new coronary pneumonia using various techniques including plasma metabolomics