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New approach to identify and treat aggressive early-stage lung cancer

 Last Update: 2022-04-24
 Source: Internet
 Author: User

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The Mount Sinai research team used a genomic network model to measure tumor aggressiveness -- distinguishing aggressive tumors from so-called "indolent" tumors that are often indistinguishable from chest CT scans -- and to identify those that inhibit Aurora kinase inhibition.

"Methods for diagnosing and treating early-stage lung adenocarcinoma are developing based on advances in the understanding of the biology and clinical activity of these tumors,

The research team used a genetically engineered mouse model to determine the role of aurora kinase in early disease progression

The researchers encourage further validation and clinical trials in human tumors

Researchers from Weill Cornell Medicine-NewYork-Presbyterian Hospital and Sema4, a patient-centric health intelligence company, participated in the study

Journal Reference :

Seungyeul Yoo, Abhilasha Sinha, Dawei Yang, Nasser K.

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