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AHA / ASA guidelines recommend qualified ischemic stroke providing a patient blood vessel within the thrombus resection (EVT), before the disease modified Rankin Scale (mRS) <2.
Premorbid substantially disabled patients (mRS≥2) of Excluded from the key EVT trial
.
However, patients with moderate to severe disability before the illness account for one-third of all ischemic stroke patients
.
In addition, a recent two-center study conducted in the United States showed that patients with pre-morbid mRS ≥ 2 accounted for 34% of real-world EVT cases.
Compared with patients with pre-morbid mRS 0-1, the mRS score ranges from pre-stroke to 90 The change of the day showed a recovery similar to the level of disability before the illness
.
A previous multicenter observational study reported similar results, but only in centers in Europe
In order to provide more evidence for such trials, a prospective randomized clinical trial is needed to determine the benefits of EVT for patients with pre-morbid disability.
Among TRACK’s 634 patients, 407 patients were included in our cohort, of which 53/407 (13.
0%) had PD
Compared with NPD patients, the adjusted probability of PD patients without cumulative disability was 5.
2 (95% CI 2.
4-11.
4, p<0.
001)
In this study of EVT treatment in patients with acute ischemic stroke in the anterior circulation, they found that compared with patients without anterior circulation disability, anterior circulation disability was related to the probability of not accumulating more disability, but also to higher The probability of death is related
.
Compared with patients without anterior circulation disability, anterior circulation disability is related to the probability of not accumulating more disability, but it is also related to a higher probability of death
.
Original source:
de Havenon A, Castonguay A, Nogueira R, et al.
Prestroke Disability and Outcome After Thrombectomy for Emergent Anterior Circulation Large Vessel Occlusion Stroke .
Neurology.
Published online September 20, 2021:10.
1212/WNL.
0000000000012827.
doi:10.
1212/ WNL.
0000000000012827Prestroke Disability and Outcome After Thrombectomy for Emergent Anterior Circulation Large Vessel Occlusion Stroke in this message