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Cerebral vein thrombosis (CVT) is a rare and serious disease
.
Its morbidity rate is on the rise, as high as 1-57/100,000/year, and its mortality rate is declining
Thrombosis in children
The sex ratio varies with age .
Newborns 5 and 6 are primarily male at first, while young adults are mainly female, and it does not persist among the elderly
.
.
Studies have shown that there are important differences between men and women in the etiology, clinical manifestations and prognosis of CVT
.
Adolescence is a very special period in life.
It is not just a transition from childhood to adulthood.
In terms of health issues, it needs to be considered separately
.
In fact, adolescence seems to be a critical age during which neurological diseases can have a huge impact on all aspects of patients’ lives
For example, the specific cause and course of adolescent arterial stroke have been shown
.
For venous thromboembolic diseases, the age distribution shows that the incidence of adolescents has reached a peak
There is no specific research on CVT during adolescence
They included 102 patients (52-9% were women; median age was 15-1 years)
.
The estimated incidence is 0-37-0-38/100,000 adolescents/year
epilepsy
The lateral sinus is the most common location for CVT (72-3%), and 29-4% of adolescents have related venous infarctions and/or hematomas
.
Most patients (94-1%) received anticoagulant therapy
Blood vessel
The most common CVT-related conditions are local infection in male patients (18-6%) and systemic disease in female patients (14-8%; P<0-001)
.
The proportion of CVT in adolescents with no identified related diseases or risk factors is very low (1-9% vs 11-4% of adults; P<0-002)
.
Adverse consequences after 1 year are more common than adults (33-3% vs 11-8%; p=0-0001)
CVT in adolescents is rare and complex, with special epidemiological characteristics , including differences in clinical manifestations and related conditions between different sexes, as well as more serious results than adults
.
Therefore, careful specialized management and follow-up are recommended
.
CVT in adolescents is rare and complex, with special epidemiological characteristics
Original source:
Devianne J, Legris N, Crassard I, et al.
Epidemiology, Clinical Features, and Outcome in a Cohort of Adolescents With Cerebral Venous Thrombosis .
Neurology.
Published online September 20, 2021:10.
1212/WNL.
0000000000012828.
doi:10.
1212 /WNL.
0000000000012828
