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Neurology: the relationship between serum magnesium levels and the risk of intracranial aneurysms

 Last Update: 2021-07-29
 Source: Internet
 Author: User

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Serum magnesium concentration is related to blood pressure regulation and vascular endothelial cell function, but its role in the pathophysiological mechanism of intracranial aneurysms is not yet clear
.

Blood vessel

Recently, an authoritative journal in the field of neurology published a research article in Neurology.
Researchers conducted Mendelian randomization analysis to explore the relationship between serum magnesium concentration and the risk of intracranial aneurysm
.

In the genome-wide association study of 23829 individuals of European descent, five single nucleotide polymorphisms closely related to serum magnesium concentration were used as genetic tools
.

The estimated genetic association of intracranial aneurysms comes from a genome-wide association study of 79429 individuals (7495 cases and 71934 controls)

Odds ratio result

A higher genetic prediction of serum magnesium concentration is associated with a lower risk of intracranial aneurysm
.

Genetic prediction is that for every 0.

It can be seen that the results of this study provide evidence support for increasing the serum magnesium concentration to reduce the risk of intracranial aneurysm and related bleeding

The results of this study provide evidence support for increasing the serum magnesium concentration to reduce the risk of intracranial aneurysms and related bleeding

Original source:

Susanna C.

Association of Serum Magnesium Levels With Risk of Intracranial Aneurysm: A Mendelian Randomization Study in this message

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