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Laryngeal dystonia (LD) is an isolated task-specific focal dystonia that selectively impairs speech production
A total of 161 subjects were studied with fMRI
Our findings suggest that the left precuneus in LD patients is the site of central short-term BoNT action, whereas the prefrontal-cerebellar axis is involved in BoNT responses in patients with intermediate treatment durations of 6-12 years
Source:
O'Flynn LC, Simonyan K.