Neurology: Risk of stroke among cancer survivors

There is growing evidence that cancer survivors may have a relatively high risk of stroke.
recently, a study published in Neurology, an authoritative journal in the field of neurology, looked at population-based, queue-based data to determine whether cancer survivors have a relatively high risk of stroke compared to non-cancer populations.
researchers searched the Pubmed, Embase and Cochrane libraries from the database's instrane until February 8, 2020, to determine a crowd-based cohort study.
used random effect models to summarize effect estimates with 95% CI.
the researchers conducted subgroup and Meta regression analyses to explore the source and stability of heterogeneity.
researchers identified 20 population-based cohort studies involving 10479,530 participants.
Overall, cancer survivors had a stroke RR of 1.66 (95% CI of 1.35-2.04; p.lt;0.001) compared to non-cancer controls, and a significant increased risk was observed in head and neck, blood, lung, pancreatic and stomach cancer survivors (all p.lt;0.05), while no significant increased risk was observed in other types of cancer.
the effect was found in women (RR is 1.38, 1.18-1.61;p.lt;0.001), younger at the time of diagnosis of cancer (RR is 2.57, 95% CI is 1.27-1.27- 5.19; p-0.009) and shorter cancer survival (≥1-2 years) (RR is 1.69, 95% CI is 1.18-2.42; p-0.004) cancer survivors are more significant.
, cancer survivors had a significant increased risk of ischemic stroke compared to hemorrhagic stroke (RR 1.53, 95% CI 1.28-1.84; p.lt;0.001).
shows that cancer plays a vital role in the onset of stroke.
because of the greater heterogeneity of the studies included, the results should be interpreted with caution.
, early prevention and effective intervention in the stroke of cancer survivors need to be noted by health decision makers.
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