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Serum neuron-specific enolase (NSE) as a biomarker for predicting prognosis in hypoxic brain injury has been the subject of many studies over the past 20 years
Serum neuron-specific enolase (NSE)
In January 2022, Kartavya Sharma et al.
Kartavya Sharma Neurology Neurology Determines NSE Threshold Predicting Adverse Outcomes After Cardiac Arrest with >95% Specificity
Data from 11 studies (n=1,982) with data at 0–24 hours, 21 studies (n=2,815) with data at 24–48 hours, and 13 studies (n=2,557) Data at 48–72 hours
The authors concluded that the highly specific NSE threshold for predicting adverse outcomes is well above the commonly used criteria
The highly specific NSE threshold for predicting adverse outcomes is well above the commonly used criteria
Original source:
Kartavya Sharma, Merin John, Song Zhang, et al.
Serum Neuron-Specific Enolase Thresholds for Predicting Postcardiac Arrest Outcome: A Systematic Review and Meta-analysis
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