Neurology: In stroke patients with renal insufficiency, intensive antihypertensive treatment may be counterproductive!

Stroke and chronic kidney disease are both very difficult diseases, and it is even more difficult to treat them when you suffer from both types of diseases at the same time

A new study published by the National Heart and Cerebrovascular Center of Japan in the journal Neurology suggests that for patients with acute cerebral hemorrhage with renal insufficiency, intensive blood pressure (systolic blood pressure 110-139 mmHg) may lead to more serious consequences

The study analyzed the death and severe disability of 974 patients with acute cerebral hemorrhage within 3 months after treatment.

1.

However, patients with mildly impaired renal function (eGFR: 60–89 ml/min/1.

Based on the eGFR classification of patients with acute cerebral hemorrhage, the difference in the outcome of enhanced or standard blood pressure reduction

2.

In patients with renal insufficiency, patients with intensive antihypertensive therapy have a higher rate of death or disability; while in patients with normal renal function or mildly impaired renal function, whether they receive intensive antihypertensive therapy or not, death within 3 months Or the risk of disability was not significantly different

Previous studies believe that for patients with acute cerebral hemorrhage, intensive antihypertensive treatment can help reduce the risk of hematoma enlargement and prevent brain damage after stroke

This study by Japanese scholars pays more attention to acute cerebral hemorrhage stroke patients with renal insufficiency.

Original source:

Mayumi Fukuda-Doi, et al.