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Soybeans have been a traditional diet for Asians for thousands of years, but it has only been about 60 years since it has appeared on the Western table as a common food
.
Now, many supermarkets in the East and the West have a lot of soy foods, such as soy milk, soy hamburgers and other vegetarian products that use soy instead of meat.
In addition to being a delicious food, compared to other foods, a soy diet can also reduce the risk of heart disease
.
Soybean can provide the nutrients needed by the human body such as protein, unsaturated fatty acids, vitamin B, fiber, iron, calcium and zinc.
The world is experiencing rapid aging, and the global prevalence of age-related cognitive decline and dementia is expected to rise substantially
.
The dysfunction caused by cognitive decline and dementia not only affects patients, but also imposes a huge burden on families and society
Prevention of brain lesions that lead to dementia may have occurred years or even decades before SCD
Flavonoids are a group of phytochemicals naturally present in plants and have long been considered powerful antioxidants
.
Considering the possible role of oxidative stress in age-related cognitive decline, flavonoids have been proposed as potentially effective agents to prevent deterioration of cognitive function
In addition, it is unclear whether different flavonoid subtypes and specific foods that contribute to flavonoid intake have different relationships with cognitive function
.
Therefore, Tian-Shin Yeh and others of Harvard University used two large prospective cohorts to comprehensively repeat the dietary assessment during more than 20 years of follow-up to investigate the relationship between flavonoid intake and subsequent SCD
.
They conducted a follow-up survey of 49,493 women in the Nurses’ Health Study (NHS) (1984-2006) and 27,842 men in the Health Professional Follow-up Study (HPFS) (1986-2002)
.
The Poisson regression method was used to evaluate the relationship between dietary flavonoids (flavonols, flavonoids, flavanones, flavan-3-ols, anthocyanins, polymeric flavonoids, and procyanidins) and subsequent SCD
They found that after adjusting for age, total energy intake, major non-dietary factors, and specific dietary factors, a higher total flavonoid intake was associated with a lower chance of SCD
.
After major non-dietary factors and specific dietary factors, higher total flavonoid intake is associated with lower SCD probability
Comparing the highest quintile and the lowest quintile of total flavonoid intake, the corresponding ORs (95% CIs) = 0.
81 (0.
76, 0.
89)
In the aggregated results, flavonoids (OR=0.
62 [0.
57, 0.
68]), flavanones (0.
64 [0.
58, 0.
68]) and anthocyanins (0.
76 [0.
72, 0.
84]) have the strongest correlation with SCD
.
The dose-response curve of flavonoids is the steepest, followed by anthocyanins
.
Many foods rich in flavonoids, such as strawberries, oranges, grapefruit, citrus juice, apples/pears, celery, peppers, and bananas, are clearly associated with a low chance of SCD
.
The significance of this study lies in the discovery: higher intake of flavonoids is good for maintaining the cognitive function of American men and women
.
From an expanded perspective, eating more soy foods, such as drinking more soy milk, may make your mind more flexible
.
Original Source:
Yeh TS, Yuan C, Ascherio A, Rosner B, Willett W, Blacker D.
Long-term Dietary Flavonoid Intake and Subjective Cognitive Decline in US Men and Women [published online ahead of print, 2021 Jul 28].
_Neurology_.
2021;10.
1212/WNL.
0000000000012454.
doi:10.
1212/WNL.
0000000000012454
