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Age-related cognitive decline is driven by a complex interaction of neurovascular and neurodegenerative diseases
Dilated perivascular space (PVS)
Here, we sought to elucidate how CMBS correlates with morphological changes in the brain (supratentorial brain volume, gray and white matter volumes, and cortical thickness), as well as other hallmarks of small vessel disease
North Manhattan Study (NOMAS), Alzheimer's Disease Neuroimaging Initiative (ADNI) and Dementia Epidemiology Study Singapore (EDIS)
- The study included 2657 participants with available MRI data and 82 autopsy cases from BARS
Source: Beaman C, Kozii K, Hilal S, et al.
Cerebral Microbleeds, Cerebral Amyloid Angiopathy, and Their Relationships to Quantitative Markers of Neurodegeneration [published online ahead of print, 2022 Feb 28].
Neurology.
2022;10.
1212/WNL.
0000000000200142.
doi:10.
1212/WNL.
0000000000200142 Beaman C, Kozii K, Hilal S, et al.
Cerebral Microbleeds, Cerebral Amyloid Angiopathy, and Their Relationships to Quantitative Markers of Neurodegeneration [published online ahead of print, 2022 Feb 28].
Neurology.
2022;10.
1212/WNL.
0000000000200142.
doi:10.
1212/WNL.
0000000000200142Leave
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