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A study published in Neurology sought to investigate whether high white matter hyperintensity (WMH) burden is associated with higher stroke severity and worse functional outcomes
METHODS: The MRI-Genie study was performed on patients with acute ischemic stroke (AIS) to obtain MR neuroimaging and National Institutes of Health stroke score data in index stroke patients, as well as modified Rankin score (MRS) 3-6 months after stroke.
Higher WMH burden may be associated with increased stroke severity, with stroke damage involving the insula, parietal, and inferior frontal regions of the left cerebral hemisphere (possibly related to language function) and temporary parietal regions of the right cerebral hemisphere ( may be related to attention)
Source: Bonkhoff AK, Hong S, Bretzner M, et al.