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White matter degeneration and healthy aging and Alzheimer's disease, cognitive impairment related
White matter degeneration and healthy aging and Alzheimer's disease, cognitive disorders cognitive disorders cognitive disorders related
White matter is generally considered to be a passive brain tissue.
White matter is mainly composed of the axon wiring of the brain; due to the fatty proteins and lipids covering the axon fibers, it has the "white" homonym
Recently published in NeuroImage NeuroImage the study found , easy to aging white matter regions retain a certain degree of plasticity, under the effect of aerobic exercise, it can be for the better, the study participants' memories may be raised
In this study , the researcher collected a sample of 180 healthy but considered inactive elderly people .
In this study , the researcher collected a sample of 180 healthy but considered inactive elderly people .
The first group : walk about 40 minutes per lesson ; the second group : participated in a dance class that gradually became more difficult within six months ; the third group : as a control for the study, it was limited to balance and stretching exercises for the purpose of Keep your heart rate low
To measure changes in white matter over time, the team used a technique called the T1w/T2w ratio, which involves MRI scans of the participants’ brains
To measure changes in white matter over time, the team used a technique called the T1w/T2w ratio, which involves MRI scans of the participants’ brains
Since T1-w and T2-w images are widely used in most studies, the team decided to combine these images to create a ratio to enhance the contrast associated with the white matter of the brain
The results of the study found that participants in the walking group and dance group had increased white matter after six months of aerobic exercise
In addition, the walking group experienced the additional benefits of improved episodic memory after the intervention and was able to recall their lifetime memories better
However, for less strenuous activities, the situation was the opposite: participants in the research team were limited to low-intensity exercises, such as stretching or balancing postures, and experienced a normal, slow white matter signal decline within six months, and there was no change in episodic memory
Six-month changes in T1w/T2w signals in the active control group, walking group, and dance group
Six-month changes in T1w/T2w signals in the active control group, walking group, and dance group
"We hope that this can promote the development of white matter aging and dementia, so that more non-pharmacological treatments and life>said study author Burzynska .
In short, the results of
this study show that the white matter areas that are prone to aging retain a certain degree of plasticity, which can be induced by aerobic exercise training .
In addition, the researchers provided evidence that the T1w/T2w signal may be a useful and widely used measurement method for studying short-term plasticity and degradation in adults
.
this study show that the white matter areas that are prone to aging retain a certain degree of plasticity, which can be induced by aerobic exercise training .
In addition, research results show that the white matter areas that are prone to aging retain a certain degree of plasticity, which can be induced by aerobic exercise training
.
The evidence provided by the researchers suggests that the T1w/T2w signal may be a useful and widely used measurement method for studying short-term plasticity and degradation in adults
.
References: Andrea Mendez Colmenares et al, White matter plasticity in healthy older adults: The effects of aerobic exercise, NeuroImage (2021).
DOI: 10.
1016/j.
neuroimage.
2021.
118305
DOI: 10.
1016/j.
neuroimage.
2021.
118305 DOI: 10.
1016/j.
neuroimage.
2021.
118305
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