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Image: Benjamin Levi, MD
Source: University of Texas Southwestern Medical Center
Researchers at the University of Texas Southwest reported in a study that blocking a molecule that introduces sensory nerves into musculoskeletal damage can prevent heterotopic ossification (HO), which is a type of The process of abnormal growth of bones in soft tissues
"Heterotopic ossification is an incredibly debilitating state, and we don't have a truly effective treatment," said Benjamin Levi, MD, the leader of the study, who is the Institute for Children’s Medical Center at the University of Texas Southwest.
HO occurs in patients with a large number of musculoskeletal injuries or who have undergone some operations
To investigate this issue, Dr.
In order to identify the signals that attract sensory nerve axons into the injury site, the researchers investigated gene activity to determine which genes may produce too much or too little protein after the injury
Sure enough, when the researchers used a genetic technique to turn off the NGF signal at the injury site, HO did not appear
Dr.
