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The patient, a 61-year-old man, went to the hematology department for difficulty swallowing.
also described a two-year history of swelling of hands and faces, as well as dryness and de-incidence of skin.
examination of the mouth and pharynx found large tongue disease, fan-shaped, tongue bow erythema, overhanging swelling.
biopsy of the dangling, the Congolese red dye found apple green double refraction suggesting amyloid deposition.
analysis of immune tissue showed that the level of the circulatory radcode light chain increased.
immune-fixed serum electrophoresis showed monoclonal peaks of 0.4 g/dL.
Free's light chain level is 56.6 mg/L (reference range is 8.3 to 27.0), the ratio of radon to light chain is 3.3 (reference range is 0.26 to 1.65) and proteinuria (24-hour urine sample 0.26g) is elevated.
bone marrow flow cytometer examination found that 0.54% of the plasma cells had atypical derometers, and the cardiac magnetic resonance imaging examination suggested that amyloid proteins were affecting the left myocardial heart muscle.
amyloid degenerative disease is characterized by abnormal protein deposition in extracellular tissue.
light-chain form of disease, extracellular tissue originates from the immunoglobulin light chain associated with plasma cells.
the patient received an introphysic bone marrow transplant and had a good response to the treatment.
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