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NEJM: Promising results for iberdomide in stage II systemic lupus erythematosus

 Last Update: 2022-04-16
 Source: Internet
 Author: User

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There are abnormalities in the regulation of multiple innate and adaptive immune pathways in patients with systemic lupus erythematosus (SLE)

Immuno -Iberdomide is a novel oral cereblon E3 ubiquitin ligase immunomodulator that promotes proteasomal degradation of Ikaros and Aiolos

In the phase II clinical study, patients were randomized to receive either oral Iberdomide (0.

A total of 288 patients were enrolled in the study, of which 81 received Iberdomide at a dose of 0.

At 24 weeks, the proportion of patients who achieved an SRI-4 response was 54% in the iberdomide 0.

Phase II clinical studies have confirmed that iberdomide 0.

Iberdomide 0.

Original source:

Joan T.

Phase 2 Trial of Iberdomide in Systemic Lupus Erythematosus.

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