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NEJM: Pimaserin is effective for dementia and psychosis caused by many reasons

 Last Update: 2021-07-27
 Source: Internet
 Author: User

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Clinically, there are many diseases that can cause dementia, such as Alzheimer's disease, Lewy body dementia, Parkinson's disease, vascular dementia, and frontotemporal dementia, which may cause symptoms such as hallucinations and delusions in patients

Vascular FDA researchers recently investigated the effects of pimaserin on the psychiatric symptoms of patients with dementia of various causes

Patients with psychiatric symptoms caused by diseases such as Alzheimer’s disease, Lewy body dementia, Parkinson’s disease, vascular dementia, and frontotemporal dementia participated in the study.

392 patients participated in the open treatment, 41 withdrew due to ineffectiveness, and the remaining 351 patients underwent follow-up trials, of which 217 (61.

Twelve people in the pimaserin group experienced recurrence of psychosis (13%), while 28 people (28%) in the placebo group had a recurrence risk ratio of 0.

Differences in risk of recurrence of psychosis between groups

Studies believe that pimaserin has a good therapeutic effect on dementia-related psychosis caused by a variety of diseases

Pimaserin has a good therapeutic effect on dementia-related psychosis caused by various diseases.

Original source:

Pierre N.

Trial of Pimavanserin in Dementia-Related Psychosis.

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