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The patient, a 29-year-old man, went to the hematology department for six months with painless progression and no itchy skin lesions.
he had no systemic symptoms, such as night sweats or weight loss.
physical examination revealed extensive freezing-like lesions on the face, back, torso and limbs (figure A).
biopsy showed that dermatation diffused and germ-like cells extended under the skin.
immunological tissue chemical analysis found that CD4, CD56 and CD123 positive cells, supporting the diagnosis of rare blood system cancerous plasma cell-like dendrites.
computer fault scans found no evidence of skin lesions.
bone marrow suction was found to have 1% tumor plasma cell-like protrusive cells.
patients received a 1-week course of treatment for dexamisong, and skin lesions were significantly reduced (figure B).
Then treated alternately with high-dose methotrexate and agasticoside, combined with eight cycles of high-dose CVAD (cyclophosphamide, chrysotyl, atomycin and dexamycin), after which the lesions were completely alleviated.
a systemic disease, although it can manifest it as skin lesions.
it is important to obtain a complete phased assessment before treatment begins, including the use of glucosticoids.
after 6 months of cure, the disease returned and the patient did not respond to further treatment.
died 27 months after his diagnosis.
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