-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
-
Cosmetic Ingredient
- Water Treatment Chemical
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
Many immune cells vital to our immune system grow in a small organ close to the heart: the thym.
The thymus is an important organ of the immune syst.
Molecular family tree analysis to identify progenitor cells
In collaboration with the laboratory of Dominic Grün (Dominic is an expert in single-cell RNA analysis), the researchers have now succeeded in characterizing the unexpected diversity of thymic epithelial cells at the transcriptional lev.
After a period of method development, Anja Nusser from Boehm's lab and Sagar from Grün's lab jointly succeeded in developing a method that connects information from the phylogenetic tree with the molecular features of individual cel.
Continuous activity of progenitor cells determines thymus composition
The researchers identified two bipotent progenitor cell populations in the thymic epithelium in their analys.
At earlier time points, mainly cortical thymic epithelial cells formed, mainly promoting T cell producti.
New treatment to increase thymus function
The sophisticated combination of a transgenic animal model from the Boehm lab and Grün's group's state-of-the-art single-cell analysis method allowed the researchers to examine the effect of increasing the proliferation of thymic epithelial cel.
"The thymus of stimulated old mice remained larger than that of unstimulated young mi.
