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Brief exposure to rapamycin has the same antiaging effects as lifelong treatment
Research scientists are increasingly focused on combating the negative effects of aging
"Currently, the most promising anti-aging drug is rapamycin, a cytostatic and immunosuppressive agent commonly used in cancer treatment and after organ transplantation
just a brief touch
The scientists tested different short-term dosing time windows in fruit flies
"These brief drug treatments in early adulthood produced protection that was as strong as continuous treatment started at the same time
One step closer to the application
"We've found a way to circumvent the need for long-term, long-term ingestion of rapamycin, so it may be more practical in humans," said Yu-Xuan Lu, Ph.
The authors concluded: It will be important to investigate whether rapamycin might achieve geriatric protection in mice and in humans who start treatment later, as the ideal treatment period should be as short as possible
Reference: "Long-lasting geroprotection from brief rapamycin treatment in early adulthood by persistently increased intestinal autophagy," Nature Aging