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    Home > Biochemistry News > Biotechnology News > Nature sub-journal: Roadmap for immune defense cells

    Nature sub-journal: Roadmap for immune defense cells

    • Last Update: 2022-08-19
    • Source: Internet
    • Author: User
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    Figure: The fully assembled PLC antigen processing machinery consists of the antigen transport complex TAP1/2, the chaperones calreticulin, ERp57 and tapasin, and the heterodimeric MHC I (heavy and light chains, cyan and green, respectively.


    Image credit: Christoph Thomas & Robert Tampé, Goethe University Frankfurt, Germany

    Organisms are often invaded by pathogens such as viruse.


    At this point, antigen processing kicks i.


    The partners that support antigen processing are calmodulin, ERp57 and tapazi.


    As research has shown, chaperones are core process components: they bring long-term stability to signposts through rigorous selectio.


    Where does the research point? "We now have a better understanding of which peptides are loaded and how this happen.


    article title

    Molecular basis of MHC I quality control in peptide-loaded complexes


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