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Cells are separated by a membrane, and proteins on the cell membrane play a very important role in transporting various cellular messag.
Although the structures of many membrane proteins, including glucose transporters, have been revealed through recent advances in structural biology, such as cryo-electron microscopy, the folding pathways by which these membrane protein structures are formed are almost completely unkno.
Glucose transporters, as the name suggests, are a group of proteins that have channels through which glucose can pa.
Specifically, we demonstrated that the domain corresponding to half of the glucose transporters located at the N-terminus has a more stable structural form than the protein that follows the C-terminal doma.
Sequence analysis of GLUT3 and other evolutionarily related sugar transporters using bioinformatics metho.
article title
Evolutionary balance between foldability and functionality of a glucose transporter