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    Home > Biochemistry News > Biotechnology News > Nature sub-journal: Human membrane proteins reach evolutionary equilibrium

    Nature sub-journal: Human membrane proteins reach evolutionary equilibrium

    • Last Update: 2022-08-11
    • Source: Internet
    • Author: User
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    Image: The folding process of the glucose transporter

    Source: Seoul National University

    Cells are separated by a membrane, and proteins on the cell membrane play a very important role in transporting various cellular messag.


    Although the structures of many membrane proteins, including glucose transporters, have been revealed through recent advances in structural biology, such as cryo-electron microscopy, the folding pathways by which these membrane protein structures are formed are almost completely unkno.


    Glucose transporters, as the name suggests, are a group of proteins that have channels through which glucose can pa.


    Specifically, we demonstrated that the domain corresponding to half of the glucose transporters located at the N-terminus has a more stable structural form than the protein that follows the C-terminal doma.


    Sequence analysis of GLUT3 and other evolutionarily related sugar transporters using bioinformatics metho.


    article title

    Evolutionary balance between foldability and functionality of a glucose transporter

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