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    Home > Biochemistry News > Biotechnology News > Nature Sub-Journal: A Previously Unknown Mechanism for Controlling Tumor Growth in Cultured Cells and Mice

    Nature Sub-Journal: A Previously Unknown Mechanism for Controlling Tumor Growth in Cultured Cells and Mice

    • Last Update: 2022-09-08
    • Source: Internet
    • Author: User
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    Image credit: Chandrasekhar Kanduri and Meena Kanduri, University of Gothenburg at Sargrenska Institute


    Researchers at the University of Gothenburg have discovered a previously unknown mechanism


    In a research article published in the journal, scientists in Gothenburg described their findings


    This protein, called HnRNPK, binds to messenger rna (mRNA), which is coded for


    Changes in tumor growth

    "Maintaining RNA isolation from these two genes can promote tumor growth


    The study also showed that, similarly, the HnRNPK protein binds to mRNAs from several other genes, preventing the formation


    This finding provides room to indirectly influence the FGF-2 growth factor, which is known to be key


    Fewer side effects

    Corresponding author Meena Kanduri, Sahlgrenska said, "Given the critical role of FGF-2 in normal human development, there are too many side effects associated with using drugs that directly target growth factors


    More research is needed to validate the portability


    Article title

    HnRNPK maintains single strand RNA through controlling double-strand RNA in mammalian cells

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