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UT Southwestern researchers have discovered a molecular pathway that causes glioblastoma to spread to tissues surrounding the bra.
"The aggressiveness of glioblastoma may be the most formidable barrier to its treatment," said Amyn Habib, .
Researchers at The University of Texas Southwestern have identified a molecular pathway that causes glioblastoma to spread to tissues surrounding the brain, and an existing drug that inhibits tumor growth in animal mode.
Researchers have long believed that a protein on the surface of cells, the epidermal growth factor receptor (EGFR), is the driver of this canc.
EGFR on glioblastoma cells can send these signals in two ways: either without prompting, in a state called constitutive signaling, or when stimulated by proteins called ligan.
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natural cell biology
