Nature Significant Progress: Study ingress monkey respiratory disease model strains infected with SARS-CoV-2!

May 26, 2020 /
Bio-ValleyBIOON / - By the end of 2019, a global outbreak of the new coronavirus SARS-CoV-2 causes respiratory diseases with a fatality rate of about 2%Following an unprecedented global outbreak, the World Health Organization declared the 2019 coronavirus disease (COVID-19) a global pandemic on March 11, 2020Although data on human diseases are steadily emerging, some aspects of SARS-CoV-2 pathogenesis can only be studied in detail in animal models, where repeated sampling and tissue collection can be madeimage source: https://cn.bing.com
In order to reveal the pathogenesis of the disease in models closer to the human body, researchers from the Virology Laboratory of the National Instituteof Sage's Institute of Allergy and Infectious Diseases recently wrote in Nature that the process and related pathology of respiratory diseasein rhesus monkeys infected with SARS-CoV-2 were presentresearchers found respiratory diseases caused by SARS-CoV-2 infections can last 8-16 daysThe researchers observed lung leaching in rhesus monkeys, a sign of human disease, using lung X-raysresearchers detected high viral loads in nasopharyngeal swabs and bronchial alveoli irrigation fluids in all animals, the researchers observed moderate disease observed in most human cases in the COVID-19 model of rhesus monkeysThe establishment of a new coronavirus disease model by the rhesus monkey as a model animal will deepen our understanding of the pathogenesis of the new coronavirus disease and contribute to the development and testing of medical countermeasures(Bio ValleyBioon.com)References:Munster, V.J., Feldmann, F., Williamson, B.Net al.
Thaly disease in rhesus macaques inoculated with SARS-CoV-2.
Nature (2020) https://doi.org/10.1038/s41586-020-2324-7