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Communications within the ecosystem glial cells and neuronal brain health is essential , but the glial cells of the brain of patients with Alzheimer's disease (AD) of β- amyloid (A [beta]) and tau in neurofibrillary The effects of accumulation and clearance are poorly understood, although people are increasingly aware that these are therapeutically important interactions
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Published in " Nature" magazine of the Massachusetts General Hospital (MGH) researchers leadership of a study identified a specific signaling molecule , the signal molecule can help change the inflammation and the immune system to prevent Alzheimer's disease
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Published in " Nature" magazine Nature "magazine led by Massachusetts General Hospital (MGH) researchers of the one study identified a specific signaling molecule , the signal molecule can help change the inflammation and the immune system to prevent Al Immunization prevention of Zheimer's disease
When neurons begin to die, the cognitive abilities associated with Alzheimer's disease decline
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When neurons begin to die, the cognitive abilities associated with Alzheimer's disease decline
"As soon begin mass death of neurons, called microglia and astrocytes known as microglia and astrocytes of brain cells - they are usually clean up the debris of cultured cells in brain cells cells - -Will be activated to cause neuroinflammation to protect the brain
In the case of Alzheimer's disease, neuronal cell death caused by amyloid beta deposits and tau tangles activates this response
.
The study found that , astrocytes derived cells are interleukin 3 (IL-3) programming microglia can be changed goodness of AD progress
"Knowing that astrocytes talk to microglia through IL-3 to educate microglia and help them reduce the severity of Alzheimer's disease may have important clinical significance," Swirski said
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"Knowing that astrocytes talk to microglia through IL-3 to educate microglia and help them reduce the severity of Alzheimer's disease may have important clinical significance," Swirski said
" It is surprising to find IL-3 in the brain in the brain ," said lead author Dr.
References : Astrocytic interleukin-3 programs microglia and limits Alzheimer's disease, Nature(2021).
DOI: 10.
References : Astrocytic interleukin-3 programs microglia and limits Alzheimer's disease, Nature Nature(2021).
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