Nature: Regulates the neural circuits of the brain that move finely

January 7, 2021 // -- Writing, screwing or throwing darts are just some of the activities that require a high level of skill.
researchers at the University of Basel and the Friedrich Michel Institute for Biomedical Research described how the brain mastered this delicate movement in the journal Nature.
brain-dry circuit map reveals which neurons control the fine motor skills of the arms and hands.
of all our motor behavior is the perfect interaction between neurons in the brain, spinal cord and muscles.
, however, which neural circuits control the fine motor skills of the arms, hands and fingers? Professor Silvia Arber's team has been working on this issue in recent work.
working at the University of Basel's Centre for Biology and the Friedrich Michel Institute for Biomedical Research (FMI) have been studying how the nervous system controls motor behavior for years.
(Photo Source: www.pixabay.com) Using mouse models, researchers have been able to demonstrate that specific areas of the brain's brain are responsible for various fine movements of the fore limbs.
to conduct the study, they applied so-called photogenetic and virological methods to mark neurons and observe their activity.
this allows the team to locate four neuron substations in the region and is related to specific functions.
, for example, one group of neurons can cause fore limbs to arrive, while another group of neurons control the processing of food.
evolution, the brain is the oldest part of the brain and a direct extension of the spinal cord.
brain is an important transition board between the brain's advanced exercise planning center and the spinal cord execution circuit.
in the spinal cord, the flow of information about movement eventually reaches motor neurons that are directly connected to muscle cells.
these, in turn, control movement by shrinking.
until recently, it was found that the brain thymus consists of many regions that contain specialized populations of functional neurons involved in controlling various forms of physical movement.
their study, Arber's team defined the tissue of neurons in the outer myelin (latRM), one of the brain-dry regions, and tracked how they communicated.
this allowed researchers to associate different behavioral activities with specific latRM neuron groups.
first author Ludwig Ruder explained: "Relatively simple fore limb movements, such as reaching for food, are done by projecting latRM neurons directly into the spinal cord.
" is controlled by latRM neurons that connect with neurons in other brain throe regions to perform more complex fore limb movements (including fingers), i.e. grab or feed food into the mouth.
connections and circuits are essential for more complex motor skills, " says Arber, a director of the University of The United States.
the group of neurons we identified in latRM controlled the motor skills of the fores limbs very specifically.
it is worth noting that the production of complex and precise fore limb movements ,such as throwing, grasping, or writing, requires communication between different brain-dry areas.
" divides neuron populations according to spatial tissue and connectivity according to different forms of motion, and provides an in-depth understanding of the function of the brain's brain and the control of motor behavior, in which case this is the fine motor skills of the arms and hands.
in humans and animals, many neuron circuits in the brain's brain are similar.
, it is possible to assume which groups of neurons control which movements, or how disease or injury impairs fine motor skills or other behaviors in humans.
() Source: Neuronal circuits for fine motor skills Original source: A functional map for diverse forelimb actions within brainstem circuitry, Nature (2021). DOI: 10.1038/s41586-020-03080-z ,