 Home > Biochemistry News > Biotechnology News > Nature: Mitochondrial fission requires protein DRP1, but not dynein

Nature: Mitochondrial fission requires protein DRP1, but not dynein

 Last Update: 2022-03-02
 Source: Internet
 Author: User

Tags

university new employment

new foamposites june 2019

Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

Mitochondrial fission, which is required for the maintenance of the mitochondrial network, relies on a GTPase called dynamin-related protein 1 (DRP1, also known as DNM1L)

Recently, it has been suggested that DRP1 is not sufficient for mitochondrial fission, while another GTPas called dynein-2 (dynamin-2, DNM2, also known as DYN2) is an important part of the mitochondrial fission complex

In a new study, researchers from the University Medical Center Göttingen, Germany report that mouse fibroblasts (hereafter referred to as dynein triple knockout cells) lack all three mammalian dyneins (DNM1, DNM2).

The related research results were published in the journal Nature on June 20, 2019

Considering that mitochondria and peroxisomes share the same fission mechanism, the researchers studied peroxisome fission and observed the same as mitochondrial fission

Thus, these findings suggest that DRP1 is essential for mitochondrial and peroxisomal fission, whereas mammalian dyneins DNM1, DNM2, and DNM3 are not

Reference: Tiago Branco Fonseca et al.

This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

Related Products

L-Ascorbate-2-Monophosphate Feed Grade

CAS No.: 109620-90-8

Feed Grade

Potassium Sorbate from reliable manufacturer

CAS No.: 590-00-1

Food Grade

Doxycycline Hydrochloride

CAS No.: 10592-13-9

Pharmaceutical Grade

Hot Tags

united states jobs(223)

jobs united states(236)

1 year treasury(277)

1 year subscription(296)

single use technology(195)

announcements today(81)

ups united states(221)

united states logo(227)

80 20 company(94)

healthy food name(42)

Hot Articles

The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.