Nature is a major development! Redsiwe is effective for rhesus monkeys infected with SARS-CoV-2!

, June 16, 2020 /PRNewswire/
-- COVID-19 continues to sweep the world and is in urgent need of effective treatment for COVID-19Although many drugs have been studied, approved and reused, preclinical data from animal models can guide the search for effective treatments by excluding treatments without invivityremdesivir (GS-5734), a nucleotide simulation pre-drug with extensive antiviral activity, is currently under study in a clinical trialOF COVID-19and has recently been granted emergency use by the U.SFood and Drug AdministrationIn animal models, Redsiwetreatment is effective for MERS-CoV and SARS-CoV infectionsIn in vitro experiments, Redsewe inhibited the replication of SARS-CoV-2Photo Source: NatureResearchers from the National Institutes of Allergy and Infectious Diseases at the National Institutes of Health recently studied Redsewe's efficacy in the treatment of sars-CoV-2 infection in rhesus monkeys, published in Nature, entitled "Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2"researchers found that 12 hours after the first administration, the animals treated with Redsewe showed no signs of respiratory disease, with x-rays showing decreased lung immersion and reduced viral drops in bronchopulmonary alveoliHowever, Redsiwetreatment did not reduce the loss of the upper respiratory tract virusAn autopsyafter the animals died and found that the animals that Redsewe treated had a lower lung virus load and less damage to the lungsTherefore, the early start of Redsivir treatment has clinical efficacy in rhesus monkeys infected with SARS-CoV-2 Although the rhesus monkey model does not fully represent the serious disease observed in patients with COVID-19, the researchers believe their data support the early start of Redsivir treatment in patients with COVID-19 to prevent progression of pneumonia (Bio ValleyBioon.com) References: Williamson, B.N., Feldmann, F., Schwarz, B et al.
Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2.
Nature (2020) https://doi.org/10.1038/s41586-020-2423-5