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Nat Med: What is the effect of β-thalassemia adult globin lentiviral gene therapy?

 Last Update: 2022-01-07
 Source: Internet
 Author: User

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Beta-thalassemia is a hereditary anemia caused by lack or insufficiency of the beta chain of hemoglobin

Recently, a research article was published in the top medical journal Nature Medicine.

In this phase I clinical trial (NCT01639690), these patients received reduced intensity treatment (RIC) globin TNS9.

There were no accidental safety issues during the handling and infusion of cell products

stem cell

It can be seen that these relevant results emphasize the need to closely monitor β-thalassemia patients receiving treatment with globin carriers

These related results emphasize the need to closely monitor β-thalassemia patients receiving treatment with globin carriers

Original source:

Farid Boulad,et al.

Lentiviral globin gene therapy with reduced-intensity conditioning in adults with β-thalassemia: a phase 1 trial

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