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NAR: The new program may be able to identify thousands of cancer "weaknesses" from more than 700 different types of cancer cells

 Last Update: 2021-06-01
 Source: Internet
 Author: User

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News from May 28, 2021 // - When the state of one gene exposes the vulnerability of the cell to the disturbance of the second gene, such as chemical inhibition, a weak link will appear at this time, and this link has become The entry point for precision oncology research can help develop new therapies for the treatment of many cancers.

Nucleic Acids Research scientists from Queen’s University and other institutions have identified the weaknesses of thousands of cancers by analyzing more than 700 different types of cancer cells.

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Image source: https://academic.

In the future, researchers may be expected to help develop new methods to block the proliferation and spread of cancer cells by using current drugs, while also providing new targets for the development of new drugs.

Researcher Dr.

Understanding the molecular fingerprint of cancer may help develop new methods to find the most accurate and effective drugs for the treatment of patients; and the research work in this article has taken a step towards more effective and personalized cancer treatments, and may ultimately save a variety of cancer patients.

SynLeGG overview.

Image source: Mark Wappett, et al.

Nucleic Acids Research

Cancer is usually caused by many mutations.

Researcher Dr.

The research in this article provides more researchers and communities with key data sets generated by cutting-edge technologies, as well as a toolbox for analyzing these data; the researchers hope to increase the coverage of these data in the future to speed up more targeted and effective Development of anti-cancer therapy

Original source:

Mark Wappett, Adam Harris, Alexander LR Lubbock, et al.

Mark Wappett, Adam Harris, Alexander LR Lubbock, et al.
oup.
com/nar/advance-article/doi/10.
1093/nar/gkab338/6275664">SynLeGG: analysis and visualization of multiomics data for discovery of cancer'Achilles Heels' and gene function relationships , Nucleic Acids Research (2021).
DOI: 10.
1093/nar/gkab338 oup.
com/nar/advance-article/doi/10.
1093/nar/gkab338/6275664">SynLeGG: analysis and visualization of multiomics data for discovery of cancer'Achilles Heels' and gene function relationships Nucleic Acids Research

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