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Movement Disorders - Brain atrophy, which progresses rapidly in neurological Wilson's disease

 Last Update: 2022-10-12
 Source: Internet
 Author: User

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Wilson's disease (WD) is an autosomal recessive disturbance of copper metabolism in which brain involvement causes neurologic symptoms that can lead to severe disability

Figure 1: Cover art of the paper

Recent evidence suggests that an increase in the concentration of the nerve filament light chain, a marker of ongoing brain damage, can predict deterioration

Figure 2: Graph of the paper results

They included patients who

Of the 57 patients, 36 had neurologic manifestations, 17 had liver manifestations, and 4 had no symptoms

The significance of the study is that it found that the rate of brain atrophy appears to be a promising marker

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