Mouse skin cells are converted into stem cells needed for embryonics

Israeli researchers report in a new issue of the American journal Cell-Stem Cells that they have successfully converted skin cells into the three main stem cells needed for early embryos in animal experiments, which can be differentiated into stem cells from tissues such as embryos, placenta and umbilical cords.researchers say the results are important not only for studying embryos and placental defects and addressing certain infertility issues, but also for the possibility of using human skin cells to create complete human embryos in the future without sperm and eggs.
As early as 2006, Japanese researchers discovered that adult skin cells could be "reprogrammed" back to a state similar to stem cells in natural embryos, with the potential to re-divide into organs and tissues known as "induced erythrogenic stem cells". In recent years, researchers have used induced erythmatic stem cells to grow a variety of cells, including heart muscle cells and liver cells, but have not yet been able to use it to grow tissue such as the placenta.
Researchers at the Hebrew University of Israel found that by importing a group of five genes into skin cells in laboratory mice, skin cells can be converted into three stem cells at the same time, which can be further differentiated into embryos, placenta, and extraterrocytic tissue such as the umbilical cord.
said researchers had previously tried to grow laboratory mouse embryos without sperm and eggs, but they used three stem cells isolated from living, developing laboratory mouse embryo-related tissue to re-cultivate laboratory mouse embryos. On the basis of this study, it is possible not to "sacrifice" live embryos, the use of skin cells can be in the test tube to create experimental mouse embryos. (
News Agency)