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    Home > Biochemistry News > Biotechnology News > Molecular Psychiatry Xiong's research group analyzes the loop mechanism of fear enhancing the jump reflex

    Molecular Psychiatry Xiong's research group analyzes the loop mechanism of fear enhancing the jump reflex

    • Last Update: 2022-10-03
    • Source: Internet
    • Author: User
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    The startle reflex is a highly conserved instinctive defensive behavior possessed by mammals, which involves the reactions of hundreds of muscles throughout the animal's body, mainly manifested as eye closure, facial and head and neck contractions, and full-body bounces, such a rapid defense paradigm can prepare



    On September 18, 2022, the journal Molecular Psychiatry published a research paper




    Professor Xiong Wei's research group of the University of Science and Technology of China has conducted a lot of research



    In this latest Molecular Psychiatry paper, the researchers first constructed an FPS model mouse, and found that the glutamatergic neural activity in RtTg was further enhanced



    Subsequent fine analysis of the DRN-RtTgP projection loop found that there was a local inhibitory microloop



    Guo Weiwei and Fan Sijia, postdoctoral fellows of the University of Science and Technology of China, are the co-first authors of the paper, and Professor Xiong Wei is the sole corresponding author of


    Illustration: Schematic diagram of the Jump Reflex and Fear Enhanced Jump Reflex Loop



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