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Adverse childhood experiences are associated with an increased risk of depression in children
Adverse childhood experiences are associated with an increased risk of depression in children
Eleonora Iob et al.
Data from the Avon Parent and Child Longitudinal Study, sample size = 3931
Data from the Avon Parent and Child Longitudinal Study, sample size = 3931
Analysis process
Analysis processPopulation-based depressive symptoms and C -reactive protein trajectories
Population-based depressive symptoms and C -reactive protein trajectoriesMost types of adverse childhood experiences were associated with elevated depressive trajectories across all early life stages, with greater associations with threat-related adversity
Most types of adverse childhood experiences were associated with elevated depressive trajectories across all early life stages, with greater associations with threat-related adversity
Association of Adverse Childhood Experiences (Prenatal to 18 Years) and CRP Trajectory (9-18 Years)
Association of Adverse Childhood Experiences (Prenatal to 18 Years) and CRP Trajectory (9-18 Years)
Bullying victimization and sexual abuse in later childhood/adolescence were associated with elevated CRP trajectories, whereas other adverse childhood experiences were not associated with inflammation
Inflammation was also not associated with depression and did not mediate the association with adverse childhood experiences
This study shows that adverse childhood experiences from before birth through adolescence are strongly associated with moderate and severe depressive symptoms in early adulthood
original source
Iob, E.
Iob, E.
, Lacey, R.
, Giunchiglia, V.
et al.
Mol Psychiatry https://doi.
org/10.
1038/s41380-022-01478-x
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