Mixed vaccination of different new crown vaccines may cause transient mild to moderate adverse reactions

Xinhua News Agency, London, May 13 (Reporter Zhang Jiawei Jin Jing) The University of Oxford, UK, released the preliminary results of a study on the 13th, showing that subjects were vaccinated with two major new crown vaccines currently in use in the UK, and both doses were used with normal doses.

According to Oxford University, this research project uses a mixture of the new crown vaccine jointly developed by Oxford University and AstraZeneca Pharmaceuticals, and the new crown vaccine jointly developed by Pfizer and German Biotech.

Preliminary results show that under the premise that the two doses are given 4 weeks apart, whether it is to receive one dose of AstraZeneca vaccine first, then one dose of Pfizer vaccine, or to reverse the order of the two doses, both are given the same amount as the regular two doses.

Matthew Snape, the lead scientist of the project and an associate professor at Oxford University, said that preliminary data analysis did not show that there are other safety concerns or signs of mixed vaccination with different vaccines, and the current analysis results at this stage are still unable to determine the immunization after mixed vaccination.

In addition, the team said that since the subjects in this phase of the trial are mainly people aged 50 years and above, it is also possible that adverse reactions caused by mixed vaccination have a higher chance of appearing in lower age groups.

This pilot project led by the University of Oxford has received funding support from the British government, mainly to explore whether different types of new crown vaccines can be more flexibly mixed and used.

At present, many countries in the world are facing the pressure of insufficient supply of new crown vaccine, especially in low-income countries that the problem of "a dose is difficult to find" has attracted widespread attention.