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The most common malignancy in women is breast cancer
.
In 2020, 2.
Lifetime exposure to higher estrogen increases the risk of breast cancer
Migraine is a common primary headache disorder that is more common in women than men and usually begins during adolescence, most affecting people between the ages of 35 and 45
.
Estrogen plays an important role in migraine pathogenesis, and estrogen causes migraine through two distinct pathways: estrogen withdrawal migraine or migraine associated with estrogen fluctuations
Estrogen may play a role in the pathogenesis of migraines and breast cancer, and research shows a link between them
.
Migraine is likely to play a protective role in breast cancer risk
A total of 10 studies were included in this study, of which 5 were cohort studies and 5 were case-control studies
.
.
Figure 2 presents the results of a random-effects meta-analysis and pooled adjusted RR for migraine and breast cancer associations stratified by study design
.
According to the results, there was a statistically significant inverse relationship between migraine and breast cancer in the case-control study[ HR 0.
Figure 2 In a case-control study, there was a statistically significant inverse relationship between migraine and breast cancer, HR0.
Overall, this analysis demonstrated a statistically significant inverse relationship between migraine and overall breast cancer risk
.
Although case-control studies suggest an inverse association between migraine and breast cancer risk, cohort studies do not support an inverse association between migraine and breast cancer
There was a statistically significant inverse relationship between migraine and overall breast cancer risk
Original source:
Elahe Hesari, et al.
PLOS ONE | https://doi.
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