Middle-life thopress pressure control helps reduce the risk of future brain injury

A new study published recently in the Journal of European Heart suggests that higher-than-normal blood pressure in older adults is associated with broader brain damage.
, the study found a strong link between thyspresso pressure before age 50 and brain damage in later life, even if it was within the normally considered healthy range.
findings come from a study of 37,041 participants from the British Biolibrary, the general population between the ages of 40 and 69, who had access to medical information, including MRI brain scans.
Karolina Wartolowska, a clinical researcher at the Stroke and Dementia Prevention Centre at the University of Oxford in the UK, carried out the study to look for "white high-intensity" (WMH) damage in the brain.
these appear brighter areas in MRI scans, indicating damage to small blood vessels in the brain that increase with age and blood pressure.
WMH increases the risk of stroke, dementia, physical disability, depression and reduced thinking skills. Dr Wartolowska,
The linear relationship between high white matter strength and complications of blood pressure, age, sex and cardiovascular risk factors, said: "Not all people experience these changes with age, but more than 50 per cent of patients over 65 and most people over 80 do not have high blood pressure, but as blood pressure rises, this change is more likely to occur and become more likely to become more severe."
researchers collected information about participants between March 2006 and October 2010, and follow-up data, including MRI scans, between August 2014 and October 2019.
researchers adjusted this information by taking into account risk factors such as age, sex, smoking, diabetes, diastolic and systolic stress.
systolic blood pressure is the maximum blood pressure reached by the heart each time it beats, and the highest blood pressure measurement.
to compare the size of white mass density between people, and to adjust the size of people's brains slightly differently, we divided the volume of WMH by the total accumulation of white mass in the brain," the study said.
way, we can analyze the load of WMH, the ratio of WMH volume to total white mass volume," Dr Wartolowska said.
found that high-load WMH is closely related to current systolic pressure, but the strongest association is in the past, especially in people under 50.
any increase in blood pressure, even if the systolic pressure is less than 140 mmHg and the espresso pressure is less than 90 mmHg, is associated with an increase in WMH, especially when people are taking medications to treat high blood pressure.
In the normal blood pressure group layered by age, the increase in white mass high intensity systolic pressure increased by 1.126 times for each 10mmHg higher than normal range, and the proportion of WMH load increased by 1.106x for every 5mmHg increase for espresso pressure.
In the top 10% of people with the highest WMH load, 24% of the load can be attributed to systolic pressure of more than 120mmHg and 7% to throopress pressure of more than 70mmHg, reflecting the fact that the rate of increased systolic pressure in older patients is higher than throopathic pressure.
two important findings," said Dr. Wartolowska, a researcher at the University of New South China.
, the study showed that thusion pressure in people aged 40 to 50 was associated with wider brain damage years later.
means not only systolic pressure, espressopress pressure is also important to prevent brain tissue damage.
Many people may think that high blood pressure and stroke are diseases in the elderly, but our results suggest that if we want to keep our brains healthy by the age of 60 or 70, we may have to make sure that our blood pressure, including those of thread, stays within the healthy range at the age of 40 or 50.
important finding of the study is that any increase in blood pressure beyond the normal range is associated with a higher amount of white mass density.
showed that even a slight increase in blood pressure before it met the criteria for treating high blood pressure can cause damage to brain tissue.
So, in order to ensure that white matter is best prevented in later life, especially in early middle-life, even if the threaded pressure is less than 90 mmHg, it may be necessary to control thuding pressure, and in later years it may be more important to control systolic pressure.
: Karolina Agnieszka Wartolowska, Alastair John Stewart Webb. Midlife blood pressure is associated with the severity of white matter hyperintensities: analysis of the UK Biobank cohort study. European Heart Journal, 2020; DOI: 10.1093/eurheartj/ehaa756MedSci Original Source: MedSci Original Copyright Notice: All text, images and audio and video materials on this website that indicate "Source: Mets Medicine" or "Source: MedSci Original" are owned by Metz Medical and are not authorized to reproduce, and any media, website or individual must indicate "Source: Mess Medicine" when authorizing their reprint.
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