"Middle-aged people are not as good as before"
"Metabolism drops, drinking water makes you fat"
Everyone to middle-aged fat friends, are you still using "decreased metabolic rate" to wash the ground for your weight loss?
Sorry, a "Science" paper that was just launched today (August 13) stated:
Metabolic rate does not carry this pot!
This paper is sponsored by the Chair Professor of the School of Pharmacy, Shenzhen University of Technology, Chinese Academy of Sciences, the Chief Scientist of the Energy Metabolism and Reproductive Research Center, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, John Spikeman's team, and the Associate Professor of Evolutionary Anthropology, Duke University.
The scale and scope of this study are unprecedented: the subjects come from 29 countries, a total of more than 6,400 people, the oldest is 95 years old, and the youngest is only 8 days old
They drew a curve of changes in energy metabolism during a long human life
Subvert cognition!
Subvert cognition! You can’t lose weight anymore, you can’t blame your metabolism
You can’t lose weight anymore, you can’t blame your metabolism It can be seen from this graph that a person's total energy expenditure increases rapidly during infancy, remains stable for most of adulthood, and then begins to decline around the age of 60
After calibrating the data, it can be seen that the energy consumption of babies rises rapidly within one year after birth, and reaches the peak of metabolism in their lifetime
Within a unit of body weight, the metabolic rate of babies can even be 50% higher than that of adults
After a rapid increase in the early stages of infancy, the metabolic rate will slow down at a rate of about 3% per year until about 20 years old, and then stabilize
So far began a long period of plateau
In the youth and middle age of 20-50 years old, people's metabolic rate and energy expenditure are very stable
It wasn't until around the age of 60 that the human metabolic rate began to slowly decline at a rate of 0.
How about it? Is it different from everyone's imagination?
In our opinion, the metabolic rate has not increased significantly during adolescence in all aspects
The 25 or 30-year-olds considered to be the “start of the downhill road” did not show a significant decrease in metabolic rate
How to explain this: When we were younger, we didn't get fat no matter what we ate, but when we were middle-aged, we would grow flesh when we drink cold water?
In this regard, one of the main corresponding authors of the paper, Professor John Spikeman, said: "After the age of 30, the body's various functions have declined and the waistline has become thicker.
"In their 30s and 40s, people usually feel that they are slowing down; when menopause comes, your speed will be slower, but your metabolic rate will not change at these times
The significance of this study for weight loss may lie in-"This study can estimate energy requirements, and people can more accurately calculate how much food they need to eat to ensure nutrition and avoid weight gain
To enlarge the pattern a bit more, only by understanding the energy demand of the population can we know how much food we need to produce and where the red line of food security is
.
Why send Science?
Why send Science? Data sharing in the scientific community has done things that a single team can't do!
Data sharing in the scientific community has done things that a single team can't do! Metabolism is an important subject of life activities
.
But surprisingly, scientists have never known how the human body consumes energy
.
This is because conventional research methods usually only measure the basic metabolic rate of the human body, that is, the energy consumed by the human body for important basic functions such as breathing, digestion, and pumping blood
.
And this part of energy only accounts for 50% to 70% of the body's total daily energy consumption
.
In addition to simply being "alive," we also exercise, do housework, and perform mental tasks such as reading and writing.
These will consume energy, and even emotionally and restlessly will increase energy consumption
.
The “dual-labeled water” technology used in this study allows the subjects to drink water labeled with stable isotopes, and then detect the amount of isotope excreted from urine and blood within a certain period of time to calculate the average daily consumption of individuals.
How much energy
.
This makes it possible to measure the daily energy consumption of human beings in a freely active state outside the laboratory
.
However, this technology, which was born in the 1980s, is very expensive
.
Therefore, it was rarely used in large-scale research in the past
.
In the past few years, the research team has spent a lot of time and energy to build a large database that brings together 6,421 test results from 29 countries, covering different regions, ages and genders
.
This was the result of this heavy paper that I saw today
.
"For a huge database, integrating and managing data is the most difficult part.
We designed a new equation to convert the data analyzed in different ways in different laboratories into a common method, which answered that a single research team could not answer.
The issue
.
" As the main person in charge of the International Atomic Energy Agency's "Double Standard Water" database project, Spikeman said
.
Evaluation of opinion articles published at the same time in "Science" magazine: This study provides important new insights for the study of human metabolism
.
The outstanding collaborative spirit of the team made this research of unprecedented scale and scope possible
.
Related paper information:
DOI: 10.
1126/science.
abe5017
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