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On April 28, Microchip released an announcement stating that its partner Huya Bio-International Co.
Chidamide is the world's first subtype-selective histone deacetylase (HDAC) inhibitor and the world's first oral administration approved for the treatment of peripheral T-cell lymphoma and combined endocrine drugs for the treatment of estrogen receptor-positive breast cancer The drug, targeting class I histone deacetylase (HDAC), induces cell cycle arrest, inhibits the expression of a variety of oncogenes, regulates the acetylation of PD-L1, and enhances the activity of immune checkpoint inhibitors.
Peripheral T-cell lymphoma (PTCL) is a group of highly heterogeneous abnormal malignant proliferation of lymphocytes.