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    Home > Biochemistry News > Biotechnology News > microbe helps microbe! Some of the viruses that cause cancer suppress the immune system with the help of common bacteria

    microbe helps microbe! Some of the viruses that cause cancer suppress the immune system with the help of common bacteria

    • Last Update: 2022-09-20
    • Source: Internet
    • Author: User
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    Gut bacteria have far-reaching health effects by aiding digestion, providing nutrients and metabolites, and working with the immune system to fight off pathogens


    A new study by researchers at the University of Chicago suggests that some symbiotic bacteria promote the development of leukemia caused by the mouse leukemia virus (MuLV) by inhibiting the adaptive anti-tumor immune response in animals


    Dr.


    Cancer is often thought to be the result of spontaneous mutations that cause cells to grow and multiply out of control, forming tumors


    Some cancer-causing retroviruses use gut microbes to spread and replicate


    In the new study, the researchers wanted to understand whether commensal bacteria, in addition to assisting in virus-induced cancer replication, influenced their development


    Virus-induced cancer cells all express viral antigens, or molecules that label them as hosts, making them targets


    The team conducted a series of experiments with specially designed immunodeficient mice, so they lacked an adaptive immune system


    The researchers then found that the symbiotic bacteria induced three genes


    "Now we have to figure out what's so special about bacteria that have these traits," she says


    essay

    Gut commensal bacteria enhance pathogenesis of a tumorigenic murine retrovirus


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