Methotrexate intensive therapy can effectively relieve early rheumatoid arthritis
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Last Update: 2020-07-05
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Source: Internet
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Author: User
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research by Jacobs, a scholar at Utrecht University Medical Center in the Netherlands, found that in the early stages of rheumatoid arthritis (RA), methotrexate (MTX) intensive treatment for patients could be significantly improved by computer programs(Ann Rheum Dis 2007, 66: 1409)this is a two-year, multicenter open trial involving 299 patients with early RA who were randomly assigned to the MTX intensive treatment group or the MTX routine treatment groupPatients in the intensive treatment group visited the clinic once a month, and the researchers used a designed computer program to adjust the patient's MTX dosethe pre-defined individualized treatment responsestandardIf the patient still does not produce sufficient response sourcing the maximum tolerable dose of MTX treatment, consider adding cyclosporine AThe results showed that in the intensive treatment group, 76 patients (50%) received at least one stage of remission during the two-year trial, compared with 55 (37%) in the regular group(Liu Xiaochun)
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